LDLR Antibody MAB2148-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemLDLR Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberMAB2148-100
Quantity100 ug (also 25 ug, 500 ug)
ApplicationsELISA Development,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,ELISA Capture (Matched Antibody Pair),CyTOF-ready,Functional Assay,ELISA Capture
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman
TargetLDLR
IsotypeIgG1
Clone472413
HostMouse
ImmunogenChinese hamster ovary cell line CHO-derived recombinant human LDLR, Ala22-Arg788, Accession # P01130
NCBI Full Gene Namelow density lipoprotein receptor
NCBI Gene AliasesFH, LDLCQ2, FHCL1, FHC
ClonalityMonoclonal
PurityProtein A or G purified from hybridoma culture supernatant
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human LDLR in ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse (rm) LDLR, recombinant human LRP-5, or rmLRP-6 is observed.

Sizes Available: 100 ug (also 25 ug, 500 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Three positively charged binding sites on the eastern equine encephalitis virus E2 glycoprotein coordinate heparan sulfate- and protein receptor-dependent infectionNature communicationsAugust 5, 2025Alcorn MDH, Sun C, Gilliland TC Jr, Lukash T, Crasto CM, Raju S, Diamond MS, Weaver SC, Klimstra WB.Primary antibodies used were anti-ApoER2 (Sigma, WH0007804M1-100UG, clone 3H2), anti-LDLR (R&D Systems, MAB2148-100, clone 472413), anti-VLDLR (GeneTex, GTX79552, clone 1H10), or isotype control (Thermo Fisher 14-4714-82,

(2) Shifts in receptors during submergence of an encephalitic arbovirusNatureAugust 1, 2024Li W, Plante JA, Lin C, Basu H, Plung JS, Fan X, Boeckers JM, Oros J, Buck TK, Anekal PV, et al.

(3) Resistin Modulates Low-Density Lipoprotein Cholesterol Uptake in Human Placental Explants via PCSK9Reproductive sciences (Thousand Oaks, Calif.)November 1, 2022Nava-Salazar S, Flores-Pliego A, Pérez-Martínez G, Parra-Hernández S, Vanoye-Carlo A, Ibarguengoitia-Ochoa F, Perichart-Perera O, Reyes-Muñoz E, Solis-Paredes JM, Espino Y Sosa S, et al.

(4) Multiparametric platform for profiling lipid trafficking in human leukocytesCell Rep MethodsFebruary 28, 2022Pfisterer SG, Brock I, Kanerva K, Hlushchenko I, Paavolainen L, Ripatti P, Islam MM, Kyttälä A, Di Taranto MD, Scotto di Frega A, et al.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies ,, Anti-LDLR mouse (clone 472413),R&D Systems,"Cat#MAB2148-100, Accession#P01130; RRID:AB_2135125" Anti-mouse Alexa Fluor 568,Fisher Scientific,Cat#A11004; RRID:AB_2534072 "CD14 Monoclonal Antibody (Sa2-8), FITC,eBioscience

(5) VLDLR and ApoER2 are receptors for multiple alphavirusesNatureFebruary 1, 2022Clark LE, Clark SA, Lin C, Liu J, Coscia A, Nabel KG, Yang P, Neel DV, Lee H, Brusic V, et al.(clone 3H2) (Sigma WH0007804M1-100) at 10 μg ml−1, anti-human LDLR monoclonal antibody (R&D Systems MAB2148-100) at 10 μg ml−1, anti-human MXRA8 antibody (clone 2H2G12A) (MBL International W040-3) at 10 μg ml−1,

(6) Generation and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain-Fused Anticalin ProteinThe Journal of pharmacology and experimental therapeuticsMay 1, 2018Masuda Y, Yamaguchi S, Suzuki C, Aburatani T, Nagano Y, Miyauchi R, Suzuki E, Yamamura N, Nagatomo K, Ishihara H, et al.

(7) The Proprotein Convertase Subtilisin/Kexin Type 9-resistant R410S Low Density Lipoprotein Receptor Mutation: A NOVEL MECHANISM CAUSING FAMILIAL HYPERCHOLESTEROLEMIAThe Journal of biological chemistryFebruary 3, 2017Susan-Resiga D, Girard E, Kiss RS, Essalmani R, Hamelin J, Asselin MC, Awan Z, Butkinaree C, Fleury A, Soldera A, et al.

(8) Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor DegradationThe Journal of biological chemistryAugust 5, 2016Weider E, Susan-Resiga D, Essalmani R, Hamelin J, Asselin MC, Nimesh S, Ashraf Y, Wycoff KL, Zhang J, Prat A, et al.

(9) Stable engineered vascular networks from human induced pluripotent stem cell-derived endothelial cells cultured in synthetic hydrogelsActa biomaterialiaApril 15, 2016Zanotelli MR, Ardalani H, Zhang J, Hou Z, Nguyen EH, Swanson S, Nguyen BK, Bolin J, Elwell A, Bischel LL, et al.

(10) Endophilin marks and controls a clathrin-independent endocytic pathwayNatureJanuary 22, 2015Boucrot E, Ferreira AP, Almeida-Souza L, Debard S, Vallis Y, Howard G, Bertot L, Sauvonnet N, McMahon HT.

(11) Allergen challenge in vivo alters rhinovirus-induced chemokine secretion from human airway macrophagesThe Journal of allergy and clinical immunologyApril 1, 2014Karta MR, Wickert LE, Curran CS, Gavala ML, Denlinger LC, Gern JE, Bertics PJ.

(12) Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptorBloodFebruary 27, 2014Amirache F, Lévy C, Costa C, Mangeot PE, Torbett BE, Wang CX, Nègre D, Cosset FL, Verhoeyen E.

(13) Characterization of proprotein convertase subtilisin/kexin type 9 (PCSK9) trafficking reveals a novel lysosomal targeting mechanism via amyloid precursor-like protein 2 (APLP2)The Journal of biological chemistryApril 12, 2013DeVay RM, Shelton DL, Liang H.

(14) Dissection of the endogenous cellular pathways of PCSK9-induced low density lipoprotein receptor degradation: evidence for an intracellular routeThe Journal of biological chemistryOctober 16, 2009Poirier S, Mayer G, Poupon V, McPherson PS, Desjardins R, Ly K, Asselin MC, Day R, Duclos FJ, Witmer M, et al.

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LDLR Antibody

LDLR Antibody

LDLR Antibody

LDLR Antibody

LDLR Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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LDLR Antibody from R&D Systems, a Bio-Techne Brand

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