IL-18 R alpha/IL-1 R5 Antibody MAB840-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-18 R alpha/IL-1 R5 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog NumberMAB840-100
Quantity100 ug (also 25 ug, 500 ug)
ApplicationsFlow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry,CyTOF-ready
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman,Rat
TargetIL-18 R alpha/IL-1 R5
IsotypeIgG1
Clone70625
HostMouse
ImmunogenMouse myeloma cell line NS0-derived recombinant human IL-18 R alpha /IL-1 R5, Glu20-Arg329, Accession # Q13478
NCBI Full Gene Nameinterleukin 18 receptor 1
NCBI Gene AliasesIL-18Ralpha, CDw218a, IL-1Rrp, CD218a, IL-18R-alpha, IL18Ralpha2, IL18RA, IL1RRP
ClonalityMonoclonal
PurityProtein A or G purified from hybridoma culture supernatant
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects Recombinant Human IL-18 R alpha /IL-1 R5 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-1 RI, rhIL-1 RII, rhIL-1 R3, rhIL-1 R4, rhIL-1 R6, rhIL-1 R7, rhIL-1 R8, rhIL-1 R9, rhSIGIRR or recombinant mouse IL-18 R alpha is observed.

Sizes Available: 100 ug (also 25 ug, 500 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Glioblastoma cellular MAP4K1 facilitates tumor growth and disrupts T effector cell infiltrationLife science allianceDecember 1, 2023Sun JM, Fan HY, Zhu Y, Pan TT, Wu YP, Zhang DY, Hou XY.

(2) Interleukin-37 expression and its potential role in oral leukoplakia and oral squamous cell carcinomaScientific reportsMay 26, 2016Lin L, Wang J, Liu D, Liu S, Xu H, Ji N, Zhou M, Zeng X, Zhang D, Li J, et al.

(3) Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporterNature medicineJuly 1, 2015Wang J, Sun C, Gerdes N, Liu C, Liao M, Liu J, Shi MA, He A, Zhou Y, Sukhova GK, et al.

(4) Small molecules dorsomorphin and LDN-193189 inhibit myostatin/GDF8 signaling and promote functional myoblast differentiationThe Journal of biological chemistryFebruary 6, 2015Horbelt D, Boergermann JH, Chaikuad A, Alfano I, Williams E, Lukonin I, Timmel T, Bullock AN, Knaus P.

(5) Uptake of CCR7 by KIR2DS4⁺ NK cells is induced upon recognition of certain HLA-C allelesJournal of immunology researchJanuary 1, 2015Pesce S, Carlomagno S, Moretta A, Sivori S, Marcenaro E.

(6) Spinal 5-HT3 receptors mediate descending facilitation and contribute to behavioral hypersensitivity via a reciprocal neuron-glial signaling cascadeMolecular painJune 9, 2014Guo W, Miyoshi K, Dubner R, Gu M, Li M, Liu J, Yang J, Zou S, Ren K, Noguchi K, et al.

(7) Regulation of development of CD56 bright CD11c + NK-like cells with helper function by IL-18PloS oneJanuary 1, 2013Li W, Okuda A, Yamamoto H, Yamanishi K, Terada N, Yamanishi H, Tanaka Y, Okamura H.

(8) IL-1 family members IL-18 and IL-33 upregulate the inflammatory potential of differentiated human Th1 and Th2 culturesJournal of immunology (Baltimore, Md. : 1950)November 1, 2012Blom L, Poulsen LK.

(9) Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritisArthritis research & therapyMarch 24, 2011Takei S, Hoshino T, Matsunaga K, Sakazaki Y, Sawada M, Oda H, Takenaka S, Imaoka H, Kinoshita T, Honda S, et al.

(10) Glomerular accumulation of plasmacytoid dendritic cells in active lupus nephritis: role of interleukin-18Arthritis and rheumatismJanuary 1, 2008Tucci M, Quatraro C, Lombardi L, Pellegrino C, Dammacco F, Silvestris F.

(11) IL-1alpha and IL-1beta are endogenous mediators linking cell injury to the adaptive alloimmune responseJournal of immunology (Baltimore, Md. : 1950)November 15, 2007Rao DA, Tracey KJ, Pober JS.

(12) CD molecules 2006--human cell differentiation moleculesJournal of immunological methodsJanuary 30, 2007Zola H, Swart B, Banham A, Barry S, Beare A, Bensussan A, Boumsell L, D Buckley C, Bühring HJ, Clark G, et al.

(13) Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcriptionCellular immunologyMay 1, 2006Ebert EC, Mehta V.

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IL-18 R alpha/IL-1 R5 Antibody

IL-18 R alpha/IL-1 R5 Antibody

IL-18 R alpha/IL-1 R5 Antibody

IL-18 R alpha/IL-1 R5 Antibody

IL-18 R alpha/IL-1 R5 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (13)

Reviews

IL-18 R alpha/IL-1 R5 Antibody from R&D Systems, a Bio-Techne Brand

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