Human IFN-gamma R2 APC-conjugated Antibody from R&D Systems, a Bio-Techne Brand

Yes, the IFN-gamma R2 APC-conjugated Antibody has been shown to effectively detect human IFN-gamma R2 in applications such as flow cytometry, as evidenced by its use in studies involving human monocytes and EBV-transformed B cells (kong2020).

Yes, the antibody has been utilized in studies investigating interferon signaling in conditions like Down syndrome, where it was used to assess IFN-gamma R2 expression on immune cells, contributing to the understanding of autoimmune manifestations in these patients (kong2020).

The antibody demonstrates high specificity for human IFN-gamma R2, with less than 1% cross-reactivity observed with recombinant human IFN-gamma R1 in direct ELISAs and Western blots, making it suitable for precise applications (fab773a).

Yes, research has shown that IFN-gamma signaling, which can be studied using this antibody, plays a significant role in conditions like eosinophilic esophagitis, where it affects epithelial barrier function and programmed cell death, highlighting the antibody's relevance in inflammatory research (lal2024).