Description
Integrin beta-1, also known as CD29, is a protein that in humans is encoded by the ITGB1 gene. It is an integrin unit associated with very late antigen receptors. It is known to conjoin with the alpha-3 subunit to create alpha3beta1 complex that reacts to such molecules as netrin-1 and reelin. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. The protein encoded by this gene is a beta subunit