The BACE2 Antibody (Center) from MyBioSource.com is a Rabbit Polyclonal antibody to BACE2, and BAE2. This antibody recognizes Human antigen. The BACE2 Antibody (Center) has been shown to work in the following applications: ELISA, Flow Cytometry, and Western Blot.
Description
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by BACE2. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease