The PDLIM2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PDLIM2. This antibody recognizes Human, and Mouse antigen. The PDLIM2 Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene