The Pyruvate Kinase (liver/RBC) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PKL, PKLR, PKRL, and pyruvate kinase L/R. This antibody recognizes Human, Mouse, and Rat antigen. The Pyruvate Kinase (liver/RBC) Antibody has been shown to work in the following applications: Western Blot.
Description
The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]