MyBioSource.com's CD5 RMab Antibody is a Rabbit monoclonal antibody. The CD5 RMab Antibody was generated using CD5, CD5 Antigen, and Lyt-1 as the antigen. It reacts with Human.
Description
CD5 is a glycoprotein monomer with an MW of 67 kDa belonging to the scavenger receptor cysteine-rich (SRCR) family of extracellular domain-like structures, and it possesses a large cytoplasmic domain suitable for signal transduction. CD5 is a T-cell marker that also reacts with a range of neoplastic B-cells, e.g., B-cell Chronic Lymphocytic Leukemia (B-CLL), B-cell Small Lymphocytic Lymphoma (B-SLL), and Mantle Cell Lymphoma. CD5 is expressed in T-lymphocyte subsets and is modulated during cellular activation; however, it does not react with granulocytes or monocytes