The SOCS3 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to SOCS 3, SOCS3, and SSI3. This antibody recognizes Human, Mouse, and Rat antigen. The SOCS3 Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
The suppressor of cytokine signaling (SOCS) family proteins are negative feedback system that inhibits cytokine signal transduction. One of the SOCS family, SOCS3, also named as CIS3 and SSI3, is involved in inhibition of JAK/STAT pathway which regulates IL-6 signaling in vivo. SOCS3 can be rapidly trigger by a number of factors including interleukins, IFN-gamma and TNF-alpha. Pathology such as inflammatory response, wound repair and obesity and so on have been linked to SOCS3. This antibody was raised against the full-length SOCS3 of human origin