Mouse Anti-Chicken MCAM-BIOT MBS673958 from MyBioSource.com

Product Specs
ItemMouse Anti-Chicken MCAM-BIOT
CompanyMyBioSource.com
Price $375.00Supplier Page View Company Product Page
Catalog NumberMBS673958
ReactivityChicken (Ck)
ClonalityMonoclonal
NCBI Gene AliasesCD146, MUC18
NCBI Full Gene Namemelanoma cell adhesion molecule
ApplicationsFCM, IHC-fr, IHC-p, IP
ImmunogenChicken MCAM, Mr 98 kDa (protein core ?84 kDa)
Chicken MCAM, a member of the immunoglobulin superfamily of cell surface receptors, consists of the V-V-C2-C2-C2 Ig domains. It is a single chain glycoprotein with three mRNA splice variants. One has a short cytoplasmic tail, another has a long tail, and the third seems to lack transmembrane and cytoplasmic regions. It is highly homologous to gicerin, a molecule involved in neurite outgrowth and Wilm's kidney tumor progression in the chicken, and to the human melanoma progression molecule MUC18. Chicken MCAM is expressed by c-kit+ hematopoietic progenitor cells in embryonic bone marrow, thymocytes, and capillary endothelial cells. MCAM-expressing cells sorted from bone marrow are enriched in progenitors capable of differentiating into T cells when transferred into the appropriate thymic microenvironment. MCAM has been proposed to be involved in cellular adhesion and homing processes.1
Antibody TypeSecondary
HostMouse
CloneC264
Molecular Weight71,607 Da
IsotypeIgG2b kappa
TargetMCAM
FormatBiotin (BIOT) Conjugate
Conjugate/TagBiotin (BIOT)
Quantity0.5 mg