The LPAM-1(Integrin alpha4, CD49d) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CD49d, Integrin alpha 4, and ITGA4. This antibody recognizes Human antigen. The LPAM-1(Integrin alpha4, CD49d) Antibody has been shown to work in the following applications: Western Blot.
Description
Integrins a-4/beta-1 (VLA-4) and a-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin a-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin a-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells