Mouse Anti-Chicken CD8a-FITC MBS673975 from MyBioSource.com

Product Specs
ItemMouse Anti-Chicken CD8a-FITC
CompanyMyBioSource.com
Price $410.00Supplier Page View Company Product Page
Catalog NumberMBS673975
ReactivityChicken (Ck)
ClonalityMonoclonal
NCBI Gene Aliaseszgc:136643
NCBI Full Gene NameCD8a molecule
ApplicationsFCM, IHC-fr, IHC-p, IP
Immunogenalpha chain of chicken CD8 (Mr 34 kDa)
In the chicken, the CD8 molecule is present in two forms: (i) a homodimer of two alpha chains, and (ii) a heterodimer of an alpha chain and a beta chain.1,2 Chicken CD8 is expressed on approximately 80% of thymocytes, 45% of blood mononuclear cells and 50% of spleen cells, but <1% of cells in the bursa and bone marrow.1 While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8 alpha - and CD8 beta -chains, a relatively large proportion of the CD8+ TCR- gamma delta cells in the spleens of embryos and young chicks express only the alpha -chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved, but there is a population of TCR- gamma delta CD8 alpha beta cells in the chicken that is not found in rodents.3 MAb 3-298 recognizes the CD8 alpha chain of both the chicken and turkey.4
Antibody TypeSecondary
HostMouse
Clone3-298
Molecular Weight24,017 Da
IsotypeIgG2b kappa
TargetCD8 alpha
FormatFluorescein (FITC) Conjugate
Conjugate/TagFITC
Quantity0.5 mg