The HSD17B2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human, Mouse, and Rat antigen. The HSD17B2 Polyclonal Antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
17beta-HSD2 (17beta hydroxysteroid dehydrogenase type 2) belongs to the 17beta-HSD family of proteins that regulate the availability of steroids within a tissue. 17beta-HSD2 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and testosterone. Due to the affects that 17beta-HSD2 has on the availability of estrogen, it has been extensively investigated for playing a possible role in breast tumor development, colon cancer development and the pathophysiology of endometriosis