Mouse Anti-Human CD33-APC Antibody MBS674235 from MyBioSource.com

Product Specs
ItemMouse Anti-Human CD33-APC Antibody
CompanyMyBioSource.com
Price $350.00Supplier Page View Company Product Page
Catalog NumberMBS674235
Quantity100 Tests
ApplicationsFlow Cytometry, Immunohistochemistry (Frozen Sections), Immunoprecipitation, Western Blot
Conjugate/TagAllophycocyanin (APC)
FormatAllophycocyanin (APC) Conjugate
ReactivityHuman
TargetCD33
IsotypeIgG1
Molecular Weight39,825 Da
CloneWM53
HostMouse
ImmunogenHuman CD33
CD33 is a 67 kDa type I transmembrane glycoprotein and a member of the sialoadhesin family of cell surface receptors. It is absent from pluripotent stem cells but appears on myelomonocytic precursors after CD34. It then continues to be expressed on both the myeloid and monocyte lineages, although it is absent on granulocytes. While it has been reported that CD33 can function as a sialic acid-dependent cell adhesion molecule, cells expressing CD33 require desialylation before they can bind cells bearing the appropriate sialoglycoconjugates. This suggests that inhibitory cis interactions may regulate or block any adhesion function.1-4
NCBI Full Gene NameCD33 molecule
NCBI Gene AliasesSIGLEC-3, p67, SIGLEC3
ClonalityMonoclonal