The CD2AP Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CD2AP, and CMS. This antibody recognizes Human, Mouse, and Rat antigen. The CD2AP Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease