MyBioSource.com's anti-human CD11a-R-PE Antibody is a Mouse monoclonal antibody. It reacts with Human. This antibody has been shown to work in applications such as: Flow Cytometry, and Western Blot.
Description
Information: Human CD11a (a L integrin) complexes with CD18 (b2 integrin) to form the LFA-1 heterodimer adhesion molecule which binds to three ICAM's 1, 2, and 3, also designated CD54, CD102, and CD50 respectively. LFA-1 is expressed on lymphocytes, monocytes and neutrophils and plays a role in cell-cell adhesion. Antibody 38 recognizes the I domain of the integrin alpha L subunit (CD11a) of about 180 kd. Antibody 38 blocks binding of ICAM-1 and ICAM-3 to LFA-1 at 5-10 mg/ml