The MSH3 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to MSH3. This antibody recognizes Human, Mouse, and Rat antigen. The MSH3 Polyclonal Antibody has been shown to work in the following applications: ELISA, and Immunohistochemistry.
Description
The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer