The anti-human CD45 RO-R-PE Antibody from MyBioSource.com is a Mouse Monoclonal antibody to PTPRC. This antibody recognizes Human, and Non-Human Primate antigen. The anti-human CD45 RO-R-PE Antibody has been shown to work in the following applications: Flow Cytometry.
Description
Information: Human CD45 is expressed on all cells of hematopoietic origin, except erythrocytes. CD45 is a transmembrane tyrosine phosphatase which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing of exons 4-7 of a single gene coding for the various N-terminal peptide segments. The CD45RO isoform contains none of the alternatively spliced exons and is present on most thymocytes, a subpopulation of resting (memory) T cells within both CD4 and CD8 subsets as well as on monocytes and granulocytes. CD45RO plays an essential role in lymphocyte activation. Antibody UCHL1 recognizes the CD45RO isoform of about 180 kd