The MOUSE ANTI HUMAN CD29:RPE Antibody from MyBioSource.com is a Mouse Monoclonal antibody to CD29, GPIIA', integrin beta 1, integrin, beta 1a, and ITGB1. This antibody recognizes Human antigen. The MOUSE ANTI HUMAN CD29:RPE Antibody has been shown to work in the following applications: Flow Cytometry.
Description
Mouse anti Human CD29 monoclonal antibody, clone 4B7R recognizes the human integrin beta 1 subunit, also known as CD29, a ~130kDa (red) 115kDa (non-red) single pass type I transmembrane glycoprotein expressed by most leucocytes and mesenchymal stem cells. Integrin receptors are involved in the regulation of a variety of important biological functions, including embryonic development, wound repair, hemostasis and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. Surface expression of CD29 on human natural killer cells can be reduced by pretreatment with the glutathione-S-transferase inhibitor diethyl maleate (Horvath-Arcidiacono et al. 2003)