Mouse Anti-Chicken CD8a-PE MBS673963 from MyBioSource.com

Product Specs
ItemMouse Anti-Chicken CD8a-PE
CompanyMyBioSource.com
Price $285.00Supplier Page View Company Product Page
Catalog NumberMBS673963
Quantity0.1 mg
ApplicationsFlow Cytometry; Immunohistochemistry (Acetone Fixed/Frozen Sections); Immunoprecipitation
Conjugate/TagR - phycoerythrin (R - PE)
FormatR - phycoerythrin (R - PE)Conjugate
ReactivityChicken
TargetCD8 alpha
IsotypeIgG2b kappa
Molecular Weight24,017 Da
CloneEP72
HostMouse
Antibody TypeSecondary
Immunogenalpha chain of chicken CD8 (Mr 34 kDa)
In the chicken, the CD8 molecule is present in two forms: (i) a homodimer of two alpha chains, and (ii) a heterodimer of an alpha chain and a beta chain.1,2 Chicken CD8 is expressed on approximately 80% of thymocytes, 15% of blood mononuclear cells and 50% of spleen cells, but <1% of cells in the bursa and bone marrow.1 While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8 alpha - and CD8 beta -chains, a relatively large proportion of the CD8+ TCR- gamma delta cells in the spleens of embryos and young chicks express only the alpha -chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved, but there is a population of TCR- gamma delta CD8 alpha beta cells in the chicken that is not found in rodents.3 MAb EP72 recognizes the CD8 alpha chain
NCBI Full Gene NameCD8a molecule
NCBI Gene Aliaseszgc:136643
ClonalityMonoclonal