MyBioSource.com's AVEN Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Immunohistochemistry. The AVEN Polyclonal Antibody was generated using Aven as the antigen and it reacts with Human, Mouse, and Rat.
Description
Aven binds to both Bcl-x(L) and the caspase regulator Apaf-1, which can supported that Bcl-x(L) inhibits cell death at a late (postmitochondrial) step in the death pathway. Identified in a yeast two-hybrid screen, Aven inhibited the proteolytic activation of caspases in a cell-free extract and suppressed apoptosis induced by Apaf-1 plus caspase-9. Expressing highly in the testis, ovary, and thymus