The BACE1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to BACE1, and Beta-Secretase 1. This antibody recognizes Human, Mouse, and Rat antigen. The BACE1 Polyclonal Antibody has been shown to work in the following applications: Immunoprecipitation, and Western Blot.
Description
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene