The ELF3 antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ELF3, ERT, and ESX. This antibody recognizes Human antigen. The ELF3 antibody has been shown to work in the following applications: Immunofluorescence, and Western Blot.
Description
Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis