The anti-human CD28-R-PE Antibody from MyBioSource.com is a Mouse Monoclonal antibody to CD28. This antibody recognizes Human antigen. The anti-human CD28-R-PE Antibody has been shown to work in the following applications: ELISA, and Flow Cytometry.
Description
Information: Human CD28 is an important costimulatory molecule found on all CD4+ T cells and on about half of the CD8+ T cells. T cell activities attributed to CD28 include prevention of anergy, induction of cytokine gene transcription, stabilization of cytokine mRNA and activation of CD8+ cytotoxic T lymphocytes. the ligands for CD28 identified as CD80(B7-1) and CD86(B7-2), are immunglobulin superfamily monomeric transmembrane glycoproteins of 60 kd and 80 kd respectively. Anti-CD28 antibodies have recently been shown to have a strong adjuvant effect when conjugated to the immunogen (4). Antibody ANC28.1 recognizes CD28 expressed on human T cells and also on BHK cells transfected with human CD28. Monomeric and cross linked ANC28.1 will stimulate expression of IL-2 from CD28+ cells