The PDK1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PDK1, and pyruvate dehydrogenase kinase 1. This antibody recognizes Human, Mouse, and Rat antigen. The PDK1 Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
PDK1(pyruvate dehydrogenase kinase isoform 1) is also named as PDHK1 and belongs to the PDK/BCKDK protein kinase family.It inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism(PMID:17683942).Starvation increases islet PDK activity(PMID:11723055).This antibody is speicfic to PDK1