MyBioSource.com's MYST2 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunofluorescence, and Western Blot. The MYST2 Antibody was generated using KAT7 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.Iizuka M., J. Biol. Chem. 274:23027-23034(1999).Sharma M., J. Biol. Chem. 275:35200-35208(2000).Olsen J.V., Cell 127:635-648(2006)