MyBioSource.com's RAT ANTI MOUSE ER-MP58 Antibody is a Rat monoclonal antibody. This antibody has been shown to work in applications such as: Flow Cytometry, Immunohistochemistry, and Immunoprecipitation.
Description
Rat anti Mouse ER-MP58 antibody, clone ER-MP58 recognizes the murine antigen ER-MP58, which is expressed by all bone marrow-derived M-CSF- and GM-CSF-responsive myeloid blood cell precursors. The expression of ER-MP58 remains at a high level throughout the precursor/monocyte stage and is down-regulated upon maturation into mature macrophages. The ER-MP58 antigen is used to distinguish between early myeloid-committed cells and other haematopoietic progenitors cells in the BM. The antigen has been used as a marker of murine macrophage development in the BM. ER-MP58 is suitable for the identification of myeloid haemopoietic islands in various organs, and for embryonal studies