MyBioSource.com's NR2B Antibody: RPE is a Mouse monoclonal antibody. The NR2B Antibody: RPE was generated using GluN2B, GRIN2B, hNR3, NMDAR2B, NR2B, and NR3 as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Background Info: Detects ~166kDa. No cross-reactivity against NR2A
Scientific Background: NR2B containing receptors have been implicated in synaptic plasticity, memory formation and pain modulation (3). Studies suggest that the NR2B subunit of glutamate receptors may be potential targets for relieving pain; NR2B may be a probable target for anti-nociceptive drugs, and may also be useful as analgesics (4)