The PMS2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Pms2, and PMSL2. This antibody recognizes Human antigen. The PMS2 Antibody has been shown to work in the following applications: Immunohistochemistry.
Description
This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene