The anti-human CD54 (D2)-R-PE Antibody from MyBioSource.com is a Mouse Monoclonal antibody. This antibody recognizes Human, and Non-Human Primate antigen. The anti-human CD54 (D2)-R-PE Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Flow Cytometry.
Description
Information: Human CD54 (ICAM-1) mediates cell adhesion by binding to the integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). CD54 expression on resting peripheral blood leukocytes is weak but is upregulated on activated T and B lymphocytes and monocytes. Antibody 8.4A6 recognizes the D2 domain of the CD54 molecule of 90 kd. Antibody 8.4A6 inhibits CD54 binding to LFA-1