The anti-human CD40-R-PE Antibody from MyBioSource.com is a Mouse Monoclonal antibody. This antibody recognizes Human, and Rat antigen. The anti-human CD40-R-PE Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Flow Cytometry.
Description
Information: Human CD40 is a member of the tumor necrosis factor (TNF) receptor family and is present on all B cells except plasma cells. CD40 is also found on some epithelial cells, carcinomas and lymphoid dendritic cells. CD40 plays an important role in B cell activation and the interaction with its ligand CD154 (CD40 Ligand) is essential for isotype switching (1). The CD40-CD154 interaction appears to have a role in artherosclerosis and cardiovascular disorders (3,4,5). Antibody EA-5 recognizes the CD40 molecule of about 44 kd. Binding of cross linked EA-5 will partially activate B cells