MyBioSource.com's RAT ANTI MOUSE CD71:Low Endotoxin is a Rat monoclonal antibody. The RAT ANTI MOUSE CD71:Low Endotoxin Antibody was generated using CD71, TfR, TFR1, TFRC, and transferrin receptor as the antigen. It reacts with Mouse. This antibody has been shown to work in applications such as: Flow Cytometry, Functional Assay, and Immunohistochemistry.
Description
Rat anti Mouse CD71 antibody, clone 8D3 recognizes mouse CD71, a 95kD cell surface protein that is otherwise known as transferrin receptor. CD71 is a major iron-binding protein, which plays a key role in the transport of iron into cells that require it. In mice, CD71 is widely expressed on a variety of cells, including Sertoli cells and cells which form the blood brain barrier (BBB) in the central nervous system. Rat anti Mouse CD71 antibody, clone 8D3 recognizes native, soluble and denatured forms of murine CD71. Binding of the 8D3 antibody to CD71 does not inhibit the proliferation of cell lines tested, and does not interfere with the uptake of iron into cells. The antibody has been used as a BBB transporter vector in mice and is suitable for studying CD71 expression, and iron uptake into different tissues, in the mouse