MyBioSource.com's RUNX3 Antibody (Center) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot. The RUNX3 Antibody (Center) was generated using RUNX3 as the antigen and it reacts with Human.
Description
This gene encodes a member of the runt domain-containing
family of transcription factors. A heterodimer of this protein and
a beta subunit forms a complex that binds to the core DNA sequence
5'-PYGPYGGT-3' found in a number of enhancers and promoters, and
can either activate or suppress transcription. It also interacts
with other transcription factors. It functions as a tumor
suppressor, and the gene is frequently deleted or transcriptionally
silenced in cancer. Multiple transcript variants encoding different
isoforms have been found for this gene