CD20 Antibody MBS438102 from MyBioSource.com

Product Specs
ItemCD20 Antibody
CompanyMyBioSource.com
Price $300.00Supplier Page View Company Product Page
Catalog NumberMBS438102
Quantity0.1 mg
ApplicationsFlow Cytometry (FC/FACS)
Conjugate/TagUnconjugated
ReactivityHuman
TargetCD20
IsotypeIgG2a kappa
Molecular Weight33-37kDa
CloneB9E9
HostMouse
ImmunogenRecognizes a protein of 33-37kDa, identified as CD20 (Workshop V; Code CD20.12). B9E9 recognizes extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, B cell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in B-cell activation and cell cycle progression
NCBI Full Gene Namemembrane-spanning 4-domains, subfamily A, member 1
NCBI Gene AliasesBp35, LEU-16, CD20, S7, B1, CVID5, MS4A2
ClonalityMonoclonal