MyBioSource.com's RABBIT ANTI RAT GLUTAMATE RECEPTOR 1 (C-TERMINAL) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunoprecipitation, and Western Blot. The RABBIT ANTI RAT GLUTAMATE RECEPTOR 1 (C-TERMINAL) Antibody was generated using GLR1, GluA1, GluR1, GRIA1, and HIPA1 as the antigen and it reacts with Human, Hamster, and Non-Human Primate.
Description
MBS220876 recognises the glutamate receptor 1 (also known as AMPA) which acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.This antibody linked to immobilized Protein A immunoprecipitates detergent-solubilized receptor from brain or transfected cells