The APLP1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to APLP1. This antibody recognizes Human, Mouse, and Rat antigen. The APLP1 Polyclonal Antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described