CD63 Antibody MBS438089 from MyBioSource.com

Product Specs
ItemCD63 Antibody
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS438089
ReactivityHu, Ms
ClonalityMonoclonal
NCBI Gene AliasesLAMP-3, ME491, TSPAN30, MLA1, OMA81H
NCBI Full Gene NameCD63 molecule
ApplicationsWB, ELISA, FCM, IF, IHC, IP
ImmunogenThe tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression
HostMouse
CloneSPM524
Molecular Weight26kDa (core protein); 30-60kDa (glycosylated)
IsotypeIgG1 kappa
TargetCD63
Conjugate/TagUnconjugated
Quantity0.1 mg