The TACSTD1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CD326, EGP40, EPCAM, EpCAM1, epithelial cell adhesion molecule, GA733-2, and HEA125. This antibody recognizes Human, Mouse, and Rat antigen. The TACSTD1 Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Epithelial cell adhesion and activating molecule (EpCAM/CD326) is a transmembrane glycoprotein that mediates Ca2+-independent, homophilic adhesions on the basolateral surface of most epithelial cells. EpCAM is not expressed in adult squamous epithelium, but it is highly expressed in adeno and squamous cell carcinomas (1). Research studies identified EpCAM as one of the first tumor-associated antigens, and it has long been a marker of epithelial and tumor tissue. Investigators have shown that EpCAM is highly expressed in cancer cells (reviewed in 2,3)