The RAT ANTI MOUSE Ly-6C Antibody from MyBioSource.com is a Rat Monoclonal antibody to Ly6c2, and lymphocyte antigen 6 complex, locus C2. This antibody recognizes Mouse antigen. The RAT ANTI MOUSE Ly-6C Antibody has been shown to work in the following applications: Flow Cytometry, Immunohistochemistry, and Immunoprecipitation.
Description
Rat anti Mouse Ly-6C monoclonal antibody, clone ER-MP20 recognizes murine Ly-6C, a 14kD differentiation antigen, which is expressed on macrophage/dendritic cell precursors in mid-stage development (late CFU-M, monoblasts and immature monocytes), granulocytes, and on a wide range of endothelial cells and subpopulations of B- and T-lymphocytes. Rat anti Mouse Ly-6C antibody, clone ER-MP20 is able to distinguish multiple mouse blood monocyte subsets: immature Ly-6Chi monocytes are recruited to acute peripheral inflammation and develop into Ly-6C+ exudate macrophages, whereas more mature Ly-6C-/lo monocytes are precursors for tissue macrophages and dendritic cells in steady state. Rat anti Mouse Ly-6C, clone ER-MP20 can be used in conjunction with clone ER-MP12 in two colour flow cytometric analysis, to identify different stages of myeloid progenitor cells in mouse bone marrow (Leenen et al. 1990)