The ASL antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Argininosuccinate Lyase, ASAL, and ASL. This antibody recognizes Human, and Mouse antigen. The ASL antibody has been shown to work in the following applications: Immunofluorescence, and Western Blot.
Description
This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described