The GPRASP1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GASP1. This antibody recognizes Human, and Mouse antigen. The GPRASP1 Antibody has been shown to work in the following applications: ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
The G protein-coupled receptor associated sorting protein 1 (GPRASP1) is a member of the GPRASP family and is thought to modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors (1,2). GPRASP1 interacts with receptors such as the D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CNR1) and targets these proteins for degradation in lysosomes (2). Recently, it has been shown that increased GPRASP1 levels may act as a potential biomarker for breast cancer (3)