The CD74 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CD74, CD74 molecule, and Ia-GAMMA. This antibody recognizes Human antigen. The CD74 Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified