The Sodium-Iodide Symporter Antibody: RPE from MyBioSource.com is a Mouse Monoclonal antibody to NIS, SLC5A5, sodium iodide symporter, and TDH1. This antibody recognizes Human, Mouse, and Rat antigen. The Sodium-Iodide Symporter Antibody: RPE has been shown to work in the following applications: Western Blot.
Description
Background Info: Apparent mol. wt of 97kD, non-glycosylated version at 68kD. Other minor bands associated with hNIS at160kDa, and degradation products at ~30 kDa, and ~15kDa.
Scientific Background: The sodium iodide symporter (NIS) is an ion pump that actively transports iodide across the basolateral membrane into thyroid epithelial cells (1, 2). This is important step in the process of iodide organificaton and the formation of triiodothyronine and thyroxine (3)