MyBioSource.com's MOUSE ANTI BOVINE CD32:RPE is a Mouse monoclonal antibody. The MOUSE ANTI BOVINE CD32:RPE Antibody was generated using CD32b, Fc gamma RIIb, and FCGR2B as the antigen. It reacts with Bovine. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
Mouse anti Bovine CD32 antibody, clone CCG36 recognizes the bovine homologue of human CD32, one of a group of Fc receptors belonging to the immunoglobulin superfamily and involved in phagocytosis of opsonized microbes. Bovine CD32 is a single pass type 1 membrane protein of approximately 32kDa, expressed on the cell surface of most cells including B-lymphocytes, monocytes, neutrophils and afferent veiled lymph dendritic cells Chattha, K. et al. 2010. It has been shown that expression of bovine CD32 is higher on macrophages than on neutrophils. CD32 can function in an inhibitory capacity to antibody production and is the low affinity Fc receptor for IgG (FcRII), binding to the Fc region of immunoglobulin gamma Chattha et al. 2009. Mouse anti Bovine CD32, clone CCG36 is one of a number of anti bovine CD32 reagents available from MyBioSource, clone CCG36 is of interest in that it also recognizes ovine CD32 while clone CCG39 recognizes only bovine CD32