The DBF4 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ASK. This antibody recognizes Human, and Mouse antigen. The DBF4 Antibody has been shown to work in the following applications: Western Blot.
Description
Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.Kumagai H., Mol. Cell. Biol. 19:5083-5095(1999).Jiang W., EMBO J. 18:5703-5713(1999).Ota T., Nat. Genet. 36:40-45(2004)