c-Myc Oncoprotein MBS438246 from MyBioSource.com

Product Specs
Itemc-Myc Oncoprotein
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS438246
ReactivityHu, Cz, Gor
ClonalityMonoclonal
NCBI Gene AliasesbHLHe39, MRTL, MYCC, c-Myc
NCBI Full Gene Namev-myc avian myelocytomatosis viral oncogene homolog
ApplicationsWB, ELISA, FCM, IF, IHC, IP
ImmunogenThe c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment
HostMouse
CloneMYC699
Molecular Weight62-64kDa
IsotypeIgG1 kappa
Targetc-Myc Oncoprotein
Conjugate/TagUnconjugated
Quantity0.1 mg