CD35/ CR1 Antibody MBS438467 from MyBioSource.com

Product Specs
ItemCD35/ CR1 Antibody
CompanyMyBioSource.com
Price $275.00Supplier Page View Company Product Page
Catalog NumberMBS438467
Quantity0.1 mg
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
Conjugate/TagUnconjugated
ReactivityHuman, Baboon, Cynomolgus Monkey, Rhesus Monkey
TargetCD35
IsotypeIgG1 kappa
Molecular Weight210-220kDa
CloneSPM554
HostMouse
ImmunogenRecognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma
NCBI Full Gene Namecomplement component (3b/4b) receptor 1 (Knops blood group)
NCBI Gene AliasesC4BR, C3BR, CD35, KN
ClonalityMonoclonal