MyBioSource.com's TMPRSS2 Antibody (N-term) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Flow Cytometry, Immunohistochemistry, and Western Blot. The TMPRSS2 Antibody (N-term) was generated using TMPRSS2 as the antigen and it reacts with Human.
Description
TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage