The PIM2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PIM2. This antibody recognizes Human, Mouse, and Rat antigen. The PIM2 Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Immunohistochemistry.
Description
This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity