The LLGL2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to LLGL2. This antibody recognizes Human, Mouse, and Rat antigen. The LLGL2 Polyclonal Antibody has been shown to work in the following applications: ELISA, and Immunohistochemistry.
Description
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms